ماهو نزيف العين: اهم اسبابه، أعراضه، وكيفية علاجه

What is an eye hemorrhage: its main causes, symptoms, and how to treat it

The term eye bleeding may sound frightening, but in reality, it is a general description for a range of conditions that vary from superficial bleeding in the conjunctiva to bleeding inside the vitreous or under the retina, which can threaten vision. The key to dealing with eye bleeding is knowing the source of the bleeding, the underlying cause, and the speed of intervention. In this guide, we will cover everything you need to know: definitions, types, causes, diagnostic methods, treatment options, potential complications, and prevention.


Definitions and Types of Eye Bleeding

Conjunctival hemorrhage
A clear red spot on the white of the eye appears due to ruptured superficial blood vessels. It often causes concern but is rarely serious and resolves within days to weeks.

Hyphema (bleeding inside the iris or anterior to the vitreous)
The presence of blood in the anterior chamber of the eye, usually after direct trauma. It may increase intraocular pressure and requires urgent care.

Vitreous hemorrhage (bleeding inside the vitreous)
Bleeding in the vitreous manifests as large floaters or sudden vision loss. Common causes: proliferative diabetic retinopathy, retinal tears, or vascular diseases.

Subretinal / Sub-RPE hemorrhage
Bleeding under the retina or under the retinal pigment epithelium can occur in cases such as vascular collapse (e.g., wet age-related macular degeneration) or vascular tears. It threatens the macula and affects sharp vision.

Retinal hemorrhage
Bleeding within the retinal layers appears as red dots or lines associated with blood vessels and is seen on fundus examination. Common in diabetes and hypertension.

The clinical key is to determine the location: is the blood superficial, inside the eye, or behind the retina? This determines the treatment plan and the risk to vision.


Causes of Eye Bleeding — A Practical Breakdown

Eye bleeding causes range from simple temporary causes to serious, vision-threatening ones. Here is a structured list:

A) Vascular and chronic disease-related causes

  • Diabetes (Diabetic retinopathy): Proliferative diabetic retinopathy leads to the growth of fragile new vessels that bleed easily inside the vitreous or retina.
  • Hypertension: Causes small vessel ruptures in the retina (retinal hemorrhage) and may result in macular edema.
  • Wet age-related macular degeneration (Wet AMD): Growth of new vessels under the retina may bleed and affect central vision.

B) Trauma and injuries
Direct trauma to the eye (falls, blows, accidental injuries) can cause hyphema, vitreous hemorrhage, or associated retinal tears.

C) Retinal tears and retinal detachment
Retinal tears may lead to vitreous hemorrhage due to fluid or unstable vessels entering. Retinal detachment may be accompanied by bleeding and requires urgent surgical intervention.

D) Blood clotting disorders and anticoagulant drugs
Bleeding disorders (e.g., hemophilia) or taking anticoagulants (warfarin, NOACs) or antiplatelets (aspirin, clopidogrel) increase the likelihood of intraocular bleeding.

E) Tumors and abnormal vascular structures
Eye tumors or abnormal vascular growth (e.g., congenital vascular disorders or vein occlusion) may cause bleeding inside the eye.

F) Infections and systemic diseases
Vasculitis, intraocular infections (endophthalmitis), or autoimmune diseases may be accompanied by internal bleeding.

G) Other causes
Intermittent pressure factors (severe coughing, vomiting, heavy lifting) may cause superficial conjunctival bleeding or sometimes trigger internal bleeding in susceptible patients.


Clinical Presentation: What the Patient Feels

Symptoms vary depending on the location of the bleeding:

  • Conjunctival hemorrhage: Localized redness without severe pain, usually does not affect vision much.
  • Vitreous hemorrhage: Large floaters or black lines, severe vision blurring, or sudden vision loss.
  • Subretinal hemorrhage: Distortions in central vision, dark spots, or continuous blurring.
  • Hyphema: Pain or increased eye pressure with cloudy vision and presence of blood in the anterior chamber.

It is important to differentiate between transient partial vision changes and persistent changes; any sudden deterioration requires urgent evaluation.


Diagnosis: Tests and Tools Used

Determining the source of bleeding requires a set of comprehensive tests:

  1. Fundus examination
    The doctor examines the retina with an ophthalmoscope after pupil dilation; looks for neovascularization, retinal tears, venous or severe hemorrhages.
  2. Ultrasound imaging (B-scan)
    Important when opacities (e.g., dense vitreous hemorrhage) prevent retinal view; helps detect retinal detachment or hemorrhagic cavities.
  3. Fluorescein angiography
    Reveals vessel leakage and new vessel formation; useful for planning laser treatment or anti-VEGF injections.
  4. OCT (Optical Coherence Tomography)
    Provides high-resolution cross-sections of the macula and detects edema or hemorrhage without heavy pupil dilation.
  5. Laboratory tests
    Coagulation tests, blood sugar (HbA1c), blood pressure, and possibly immune or viral tests if an inflammatory or autoimmune cause is suspected.

Important note: Correct diagnosis determines the treatment plan — vitreous hemorrhage from diabetic retinopathy is treated differently from bleeding associated with a retinal tear or tumor.


Eye Bleeding Treatment: Surgical and Medical Options

Treatment depends on the cause, location, and severity of the bleeding. Main goals: stop the bleeding if possible, protect the retina, and restore vision if feasible.

1. Conservative medical treatment

  • Stabilize blood pressure and intraocular pressure.
  • Stop or adjust anticoagulant drugs after coordination with the treating physician (cardiologist/hematologist) if safe.
  • Anti-inflammatory or steroidal medications locally/systemically for inflammatory cases.
  • Rest and observation: conjunctival bleeding or mild vitreous bleeding may improve spontaneously.

2. Intravitreal injections
Anti-VEGF agents are used for bleeding due to abnormal vessels (e.g., wet AMD or diabetic retinopathy). They help reduce leakage and prevent recurrence.

3. Laser treatment
Retinal laser is used for retinal tears or ischemic areas (panretinal photocoagulation) in diabetic retinopathy to reduce oxygen demand and limit neovascular growth.

4. Vitrectomy
A surgical procedure used to remove dense vitreous blood, perform internal laser to close tears, and reattach the retina if needed. Usually used for dense hemorrhage obstructing retinal view or with accompanying retinal detachment.

5. Treating underlying causes
Manage and monitor diabetes, control blood pressure, or treat intraocular tumors if present. Addressing the cause reduces recurrence and improves visual outcomes.


When Is Urgent Surgery Needed?

  • Sudden vision loss or dense hemorrhage preventing retinal assessment.
  • Presence of retinal detachment.

Treatment Outcomes and Visual Prognosis

Results depend on the cause and delay in treatment:

  • Mild bleeding related to small tears may resolve spontaneously, and vision usually returns to baseline.
  • Deep vitreous or subretinal bleeding may lead to retinal scarring or macular damage, limiting full visual recovery.
  • Early intervention (e.g., vitrectomy when needed) increases chances of vision recovery and reduces complications.

Patients should be counseled that vision may not return to 100%, especially if macular or retinal cells were damaged prior to intervention.


Potential Complications and Why Follow-up Is Important

  • Retinal detachment or scarring can lead to permanent vision loss if untreated.
  • Formation of fibrous tissue may cause continuous traction on the retina.
  • Intraocular inflammation or infection after internal procedures (rare but serious).
  • Increased eye pressure due to hyphema or drainage blockage.

Prevention and Practical Steps to Reduce Eye Bleeding Risk

  • Monitor and control diabetes: follow HbA1c and regular ophthalmology visits.
  • Control blood pressure and cholesterol.
  • Regular retinal exams, especially for patients with diabetes or hypertension.
  • Injury prevention: wear eye protection at work and during sports.
  • Coordinate with your doctor before stopping or adjusting anticoagulants.
  • Quit smoking and follow a balanced diet rich in antioxidants.

Quick Comparison: Advantages and Disadvantages of Treatment Methods

ProcedureAdvantagesDisadvantages
Medical observationNon-surgical, suitable for mild bleedingRecovery may be slow or fibrotic deposits may increase
Anti-VEGF injectionsReduces leakage and new vesselsRequires repeated sessions, not suitable for all situations
Retinal laserTreats tears and prevents neovascular growthNot suitable if hemorrhage covers the area
VitrectomyRemoves blood and treats tears simultaneouslySurgical procedure with risks and recovery time

Case Studies and Patient Experiences

Mr. Ali — Vitreous hemorrhage due to diabetic retinopathy
Ali, a 62-year-old farmer with 20 years of diabetes, presented with sudden floaters and vision deterioration. Examination revealed vitreous hemorrhage and extensive neovascularization. He underwent vitrectomy with internal laser and anti-VEGF injection. After three months, vision improved significantly, though continued diabetes monitoring is required.

Ms. Suad — Mild conjunctival hemorrhage after a strong sneeze
Suad, in her forties, experienced sudden eye redness after a strong sneeze. Examination revealed superficial conjunctival hemorrhage. She was advised to rest and use topical anti-inflammatories, and recovered within two weeks without complications.


Frequently Asked Questions (Expanded)

  1. Does eye bleeding always mean vision loss?
    No, not always. Outcomes depend on location, cause, and treatment speed. Conjunctival hemorrhage is usually temporary, while vitreous or subretinal bleeding can threaten vision if untreated.
  2. Can retinal hemorrhage be treated with laser alone?
    Laser is effective for retinal tears and ischemic areas but may not suffice if there is dense vitreous hemorrhage, which may require surgery.
  3. Should I stop blood-thinning medication if eye bleeding occurs?
    Do not stop any medication without consulting your doctor. Coordination between cardiologist/hematologist and ophthalmologist is necessary to assess risks and benefits.
  4. When should I see a doctor immediately?
    Sudden vision deterioration, a curtain over vision, field loss, severe pain, or sudden appearance of dense floaters.
  5. Are intravitreal injections painful?
    The procedure is done under local anesthesia; patients usually feel only mild pressure. Techniques are used to minimize pain and anxiety.
  6. Does bleeding recur after treatment?
    Recurrence is possible, especially if the underlying cause (e.g., uncontrolled diabetes or hypertension) is not managed. Follow-up is necessary.
  7. What are the common side effects of surgery?
    Mild pain, temporary redness, temporary eye pressure increase, and rarely, intraocular infection.
  8. Can eye bleeding be prevented?
    Controlling chronic diseases (diabetes, hypertension) and wearing eye protection during risk activities reduce risks.
  9. Is eye bleeding more common with aging?
    Some types, like retinal hemorrhage associated with vascular disease, increase with age, but causes vary and can occur at any age.
  10. Are there promising future treatments?
    Research on longer-lasting anti-VEGF agents, improved robotic and laser surgery techniques, and better imaging technologies continues to develop.

Practical Advice for Sudden Eye Bleeding

  • Do not rub the eye.
  • Close your eye and seek urgent medical help if bleeding is severe or accompanied by vision loss.
  • If taking blood thinners, bring a list of medications to the hospital.
  • In the case of direct injury, check for other facial or head injuries and visit the emergency department.

Reliable References for Follow-up

For more detailed information, visit websites like the American Academy of Ophthalmology (AAO), the World Health Organization (WHO), and peer-reviewed articles on PubMed and Cochrane. For local references, ask your doctor for awareness pamphlets or guidelines suitable for the Egyptian context.


Conclusion

The term eye bleeding encompasses a range of conditions from superficial conjunctival hemorrhage to vitreous or subretinal bleeding that threatens vision. The key is prompt diagnosis and linking the cause to the appropriate treatment — controlling chronic diseases, using laser or injections, or surgery when needed. Regular follow-up and patient awareness of causative factors reduce the risk of deterioration. Cairo, Egypt.

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